BDBM480683 5-chloro-1-methyl-N-[6- morpholino-1-oxo-2-[rac-(2R)- 2-fluoro-3-hydroxy-3-methyl- butyl]isoindolin-5-yl]pyrazole- 4-carboxamide::US10899772, Example 33

SMILES Cn1ncc(C(=O)Nc2cc3CN(C[C@@H](F)C(C)(C)O)C(=O)c3cc2N2CCOCC2)c1Cl

InChI Key InChIKey=QRCYMPGRBGTQOS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480683   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480683(US10899772, Example 33 | 5-chloro-1-methyl-N-[6- m...)
Affinity DataKi:  51nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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