BDBM480676 5-methyl-N-[6-morpholino-1- oxo-2-[rac-(2R)-2-fluoro-3- hydroxy-3-methyl-butyl] isoindolin-5-yl]-4-oxo-pyrazolo [1,5-a]pyrazine-3-carboxamide::US10899772, Example 26

SMILES Cn1ccn2ncc(C(=O)Nc3cc4CN(C[C@@H](F)C(C)(C)O)C(=O)c4cc3N3CCOCC3)c2c1=O

InChI Key InChIKey=KPIHOTRTBZPSOT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480676   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480676(US10899772, Example 26 | 5-methyl-N-[6-morpholino-...)
Affinity DataKi:  47nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2021
Entry Details
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