BDBM480667 N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydroxy-3- methyl-butyl]isoindolin-5-yl]- 6-(trifluoromethyl)pyridine-2- carboxamide::US10899772, Example 17

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=PZCDYKIHPQQXCA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480667   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480667(US10899772, Example 17 | N-[6-morpholino-1-oxo-2-[...)
Affinity DataKi:  2.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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