BDBM480666 N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydroxy-3- methyl-butyl]isoindolin-5-yl]- 2-[rac-(3R)-3-methylmorpholin- 4-yl]oxazole-4-carboxamide::US10899772, Example 16

SMILES C[C@@H]1COCCN1c1nc(co1)C(=O)Nc1cc2CN(C[C@@H](F)C(C)(C)O)C(=O)c2cc1N1CCOCC1

InChI Key InChIKey=WBJRAJZQWXEQFY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480666   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480666(US10899772, Example 16 | N-[6-morpholino-1-oxo-2-[...)
Affinity DataKi:  7nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
Go to US Patent