BDBM480664 2-methyl-N-[6-(5-methyl-2- pyridyl)-1-oxo-2-[rac-(2R)-2- fluoro-3-hydroxy-3-methyl- butyl]isoindolin-5-yl]oxazole- 5-carboxamide::US10899772, Example 14

SMILES Cc1ncc(o1)C(=O)Nc1cc2CN(C[C@@H](F)C(C)(C)O)C(=O)c2cc1-c1ccc(C)cn1

InChI Key InChIKey=DWZQUHUVXLAKCL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480664   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480664(US10899772, Example 14 | 2-methyl-N-[6-(5-methyl-2...)
Affinity DataKi:  4.20nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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