BDBM480663 N-[6-(dimethylamino)-1-oxo-2- [rac-(2R)-2-fluoro-3-hydroxy- 3-methyl-butyl]isoindolin-5-yl]- 6-pyrrolidin-3-yloxy-pyridine- 2-carboxamide::US10899772, Example 13

SMILES CN(C)c1cc2C(=O)N(C[C@@H](F)C(C)(C)O)Cc2cc1NC(=O)c1cccc(OC2CCNC2)n1

InChI Key InChIKey=NVYISUXAXSLUKH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480663   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480663(US10899772, Example 13 | N-[6-(dimethylamino)-1-ox...)
Affinity DataKi:  5.80nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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