BDBM480662 4-hydroxy-N-[6-morpholino-1- oxo-2-[rac-(2R)-2-fluoro-3- hydroxy-3-methyl-butyl] isoindolin-5-yl]pyridine-2- carboxamide::US10899772, Example 12

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cc(O)ccn3)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=ZEUKGCNHUOEOIM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480662   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480662(US10899772, Example 12 | 4-hydroxy-N-[6-morpholino...)
Affinity DataKi:  270nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
US Patent