BDBM480658 6-cyano-N-[6-morpholino-1-oxo- 2-[rac-(2R)-2-fluoro-3-hydroxy- 3-methyl-butyl]isoindolin-5-yl] pyridine-2-carboxamide::US10899772, Example 8

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cccc(n3)C#N)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=IUIMUGYSTANSED-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480658   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480658(US10899772, Example 8 | 6-cyano-N-[6-morpholino-1-...)
Affinity DataKi:  3.90nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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