BDBM480486 6-fluoro-5-(1-(4-methoxyphenyl)piperidin-4-yl)-5H-imidazo[5,1-a]isoindole trifluoroacetate::US10899764, Example 4

SMILES COc1ccc(cc1)N1CCC(CC1)C1c2c(cccc2F)-c2cncn12

InChI Key InChIKey=OWAJGQJOJZYDLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480486   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM480486(6-fluoro-5-(1-(4-methoxyphenyl)piperidin-4-yl)-5H-...)
Affinity DataIC50: 96.2nMAssay Description:IDO1: For testing, 24 μL of enzyme (IDO1) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent