BDBM480466 N-(4-((2S,4R)-4-Amino-2-(hydroxymethyl)pyrrolidin-1-yl)-2-methylbenzo[d]thiazol-5-yl)-2-(2-fluoro-6-methoxy-3-(1-methyl-1H-pyrazol-4-yl)phenyl)pyrimidine-4-carboxamide::US10899755, Example 15

SMILES COc1ccc(-c2cnn(C)c2)c(F)c1-c1nccc(n1)C(=O)Nc1ccc2sc(C)nc2c1N1C[C@H](N)C[C@H]1CO

InChI Key InChIKey=UUUXNNKYJBRDRF-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480466   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte

US Patent

LigandBDBM480466(N-(4-((2S,4R)-4-Amino-2-(hydroxymethyl)pyrrolidin-...)Copy SMILESCopy InChI

Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2021
Entry Details
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