BDBM480459 (S)—N-(4-(3-Aminopyrrolidin-1-yl)-7-cyano-2-methylbenzo[d]thiazol-5-yl)-2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxamide::US10899755, Example 8

SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1cc(C#N)c2sc(C)nc2c1N1CC[C@H](N)C1

InChI Key InChIKey=JVCORXJKTRKEEL-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480459   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte

US Patent

LigandBDBM480459((S)—N-(4-(3-Aminopyrrolidin-1-yl)-7-cyano-2-m...)Copy SMILESCopy InChI

Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2021
Entry Details
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