BDBM480452 (R)—N-(4-(3-Aminopyrrolidin-1-yl)-2-methylbenzo[d]thiazol-5-yl)-2-(2,6-difluorophenyl)pyrimidine-4-carboxamide::US10899755, Example 1

SMILES Cc1nc2c(N3CC[C@@H](N)C3)c(NC(=O)c3ccnc(n3)-c3c(F)cccc3F)ccc2s1

InChI Key InChIKey=KHWUERINTSCRAQ-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480452   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte

US Patent

LigandBDBM480452((R)—N-(4-(3-Aminopyrrolidin-1-yl)-2-methylben...)Copy SMILESCopy InChI

Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2021
Entry Details
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