BDBM480391 (R)-5-(tert-butyl)-N-(1-(2-chloro-3-fluoro-4-(4-((1-methyl-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)phenyl)ethyl)-1,2,4-oxadiazole-3-carboxamide ::US10899753, Example 69

SMILES C[C@@H](NC(=O)c1noc(n1)C(C)(C)C)c1ccc(c(F)c1Cl)-c1ncnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=LIICPJCVDANXNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480391   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM480391((R)-5-(tert-butyl)-N-(1-(2-chloro-3-fluoro-4-(4-((...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
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