BDBM480343 US10899738, Cpd. No 408::rac-(1S,2R)-2-(1-(1-((1-(4- cyanophenyl)azetidin-3- yl)methyl)piperidin-4-yl)-2- (2-ethyl-1H-imidazol-1-yl)- 1-phenylethyl)cyclopentyl methylcarbamate

SMILES CCc1nccn1CC([C@H]1CCC[C@@H]1OC(=O)NC)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1

InChI Key InChIKey=DSOWOWNLUVRUIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480343   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480343(rac-(1S,2R)-2-(1-(1-((1-(4- cyanophenyl)azetidin-3...)
Affinity DataIC50: 3nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent