BDBM480342 US10899738, Cpd. No 407::rac-(1S,2R)-2-(1-(1-((1-(4- chlorophenyl)azetidin-3- yl)methyl)piperidin-4-yl)-2- (1H-imidazol-1-yl)-1- phenylethyl)cyclopentyl methylcarbamate

SMILES CNC(=O)O[C@H]1CCC[C@@H]1C(Cn1ccnc1)(C1CCN(CC2CN(C2)c2ccc(Cl)cc2)CC1)c1ccccc1

InChI Key InChIKey=SALXHNZPHZHXHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480342   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480342(rac-(1S,2R)-2-(1-(1-((1-(4- chlorophenyl)azetidin-...)
Affinity DataIC50: 5nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
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