BDBM480338 US10899738, Cpd. No 403::methyl ((1S,2R)-2-((S)- cyano(phenyl)(1-((1-(4- ((trifluoromethyl)sulfonyl) phenyl)azetidin-3- yl)methyl)piperidin-4- yl)methyl)cyclopentyl) carbamate

SMILES COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C(F)(F)F)CC1)c1ccccc1

InChI Key InChIKey=DCFDPTPAVDCHET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480338   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480338(methyl ((1S,2R)-2-((S)- cyano(phenyl)(1-((1-(4- ((...)
Affinity DataIC50: 7nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
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