BDBM480326 US10899738, Cpd. No 390::rac-(1S,2R)-2-(1-(1-((1-(4- cyanophenyl)azetidin-3- yl)methyl)piperidin-4-yl)-1- (3-fluorophenyl)-2-(1H- imidazol-1- yl)ethyl)cyclopentyl methylcarbamate

SMILES CNC(=O)O[C@H]1CCC[C@@H]1C(Cn1ccnc1)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1cccc(F)c1

InChI Key InChIKey=UDTLYHREMCOXLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480326   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480326(rac-(1S,2R)-2-(1-(1-((1-(4- cyanophenyl)azetidin-3...)
Affinity DataIC50: 5nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
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