BDBM480314 US10899738, Cpd. No 376::rac-3-((1S,2R)-2-(2-(1H- imidazol-1-yl)-1-(1-((1-(4- ((1-methyl-1H-pyrazol-4- yl)sulfonyl)phenyl)azetidin- 3-yl)methyl)piperidin-4-yl)- 1-phenylethyl)cyclopentyl)- 1,1-dimethylurea

SMILES CN(C)C(=O)N[C@H]1CCC[C@@H]1C(Cn1ccnc1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2cnn(C)c2)CC1)c1ccccc1

InChI Key InChIKey=PUYITSCFEXVUDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480314   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480314(rac-3-((1S,2R)-2-(2-(1H- imidazol-1-yl)-1-(1-((1-(...)
Affinity DataIC50: 6nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
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