BDBM480260 US10899738, Cpd. No 321::rac-1-((1S,2R)-2-(2-amino- 1-phenyl-1-(1-((1-(4- (phenylsulfonyl)phenyl) azetidin-3-yl)methyl)piperidin-4- yl)ethyl)cyclopentyl)-3- methylurea

SMILES CNC(=O)N[C@H]1CCC[C@@H]1C(CN)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=RXRPLAZNSINGDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480260   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480260(rac-1-((1S,2R)-2-(2-amino- 1-phenyl-1-(1-((1-(4- (...)
Affinity DataIC50: 4nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent