BDBM480230 US10899738, Cpd. No 291::rac-1-((1S,2R)-2-(2-ethyl-4- (1-((1-(4-((1-methyl-1H- pyrazol-4- yl)sulfonyl)phenyl)azetidin- 3-yl)methyl)piperidin-4-yl)- 1,2,3,4- tetrahydroisoquinolin-4- yl)cyclopentyl)-3-methylurea

SMILES CCN1Cc2ccccc2C(C1)([C@H]1CCC[C@@H]1NC(=O)NC)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2cnn(C)c2)CC1

InChI Key InChIKey=NKNUEJRAVCXOJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480230   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480230(rac-1-((1S,2R)-2-(2-ethyl-4- (1-((1-(4-((1-methyl-...)
Affinity DataIC50: 7nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent