BDBM480216 US10899738, Cpd. No 277::rac-1-methyl-3-((1S,2R)-2- (2-methyl-4-(1-((1-(4- (pyridin-4- ylsulfonyl)phenyl)azetidin-3- yl)methyl)piperidin-4-yl)- 1,2,3,4- tetrahydroisoquinolin-4- yl)cyclopentyl)urea

SMILES CNC(=O)N[C@H]1CCC[C@@H]1C1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1

InChI Key InChIKey=MYVKCHDXVPKEKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480216   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480216(rac-1-methyl-3-((1S,2R)-2- (2-methyl-4-(1-((1-(4- ...)
Affinity DataIC50: 8nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent