BDBM480141 US10899738, Cpd. No 201::US10899738, Cpd. No 202::rac-(1S,2R)-2-(2-methyl-4- (1-((1-(4-((2-methylpyridin-4- yl)sulfonyl)phenyl)azetidin- 3-yl)methyl)piperidin-4-yl)- 1,2,3,4- tetrahydroisoquinolin-4- yl)cyclopentyl acetate

SMILES CN1Cc2ccccc2C(C1)([C@H]1CCC[C@@H]1OC(C)=O)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccnc(C)c2)CC1

InChI Key InChIKey=QFIDNEUSWHCDJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480141   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480141(US10899738, Cpd. No 202 | rac-(1S,2R)-2-(2-methyl-...)
Affinity DataIC50: 5nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480141(US10899738, Cpd. No 202 | rac-(1S,2R)-2-(2-methyl-...)
Affinity DataIC50: 113nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
Go to US Patent