BDBM480105 4-((4-(3-((4-(4-cyclopentyl- 2-ethyl-1,2,3,4- tetrahydroisoquinolin-4- yl)piperidin-1- yl)methyl)azetidin-1- yl)phenyl)sulfonyl)benzoic acid::US10899738, Cpd. No 164

SMILES CCN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccc(cc2)C(O)=O)CC1

InChI Key InChIKey=ABQWFYYDUYCATL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480105   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480105(4-((4-(3-((4-(4-cyclopentyl- 2-ethyl-1,2,3,4- tetr...)
Affinity DataIC50: 8nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
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