BDBM480083 4-cyclopentyl-4-(1-((1-(4- (cyclopropylsulfonyl)phenyl) azetidin-3- yl)methyl)piperidin-4-yl)-2- ethyl-1,2,3,4- tetrahydroisoquinoline::US10899738, Cpd. No 137

SMILES CCN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CC2)CC1

InChI Key InChIKey=VYPWBZGDSHZMHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480083   

TargetMenin(Human)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM480083(4-cyclopentyl-4-(1-((1-(4- (cyclopropylsulfonyl)ph...)
Affinity DataIC50: 8nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
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