BDBM478579 3,3,3-trifluoro-1-{4-[(1R or 1S)-1-{2-[(6-{1-[(1-methylcyclopropyl)methyl]-1H-pyrazol-4-yl}-1H-benzimidazol-2-yl)amino]pyridin-4-yl}ethyl]piperazin-1-yl}propan-1-one::US10894784, Example 68.02

SMILES CC(N1CCN(CC1)C(=O)OC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cnn(CC3(C)CC3)c2)c1

InChI Key InChIKey=LGVCDHRGFZQCMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478579   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478579(US10894784, Example 68.02 | 3,3,3-trifluoro-1-{4-[...)
Affinity DataIC50: 1.5nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent