BDBM47848 4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-1-yl]carbonyl-1H-quinolin-2-one::4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazine-1-carbonyl]-1H-quinolin-2-one::4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazine-1-carbonyl]carbostyril::4-[oxo-[4-(2,3,5,6-tetramethylphenyl)sulfonyl-1-piperazinyl]methyl]-1H-quinolin-2-one::CVD-0002708::MAT-POS-916a2c5a-3::MLS000565635::SMR000152847::cid_2417657

SMILES Cc1cc(C)c(C)c(c1C)S(=O)(=O)N1CCN(CC1)C(=O)c1cc(=O)[nH]c2ccccc12

InChI Key InChIKey=WKFNCJXVHWMQRU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47848   

Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47848(4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-...)
Affinity DataIC50: 4.83E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47848(4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-...)
Affinity DataIC50: 3.75E+3nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47848(4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-...)
Affinity DataIC50: 8.46E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetSerine protease 1(Human)
Israel Institution of Biological Research

LigandPNGBDBM47848(4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-...)
Affinity DataIC50: 9.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM47848(4-[4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazin-...)
Affinity DataIC50: 8.47E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed