BDBM478206 US10894782, No 59

SMILES CN1CCN(CCNC(=O)OCC#Cc2ccc(OCc3nnc(SC4CCCC=C4)n3-c3cccnc3)cc2C)CC1

InChI Key InChIKey=LZFRXVDFWSICKZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 478206   

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM478206(US10894782, No 59)
Affinity DataIC50: 25nMAssay Description:Biomol Green (Enzo) is a bioluminescent, homogeneous assay that measures ADP formed from a biochemical reaction. Because of its high sensitivity, the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM478206(US10894782, No 59)
Affinity DataIC50: 21nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity by Biomol Green Reagent based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM478206(US10894782, No 59)
Affinity DataEC50:  890nMAssay Description:Inhibition of p97 in human HeLa cells expressing UbG76V-GFP/ODD-Luc assessed as accumulation of Ub-GFP incubated for 6 hrs by confocal microscopic an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed