BDBM478089 1-((3-(8-cyano-2-(trifluoromethyl)indolizin-5-yl)pyridin-4-yl)thio)cyclobutane-1-carboxylic acid ::US10894038, Example 7

SMILES OC(=O)C1(CCC1)Sc1ccncc1-c1ccc(C#N)c2cc(cn12)C(F)(F)F

InChI Key InChIKey=FNOCNCVIOLGNIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478089   

TargetSolute carrier family 22 member 12(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM478089(1-((3-(8-cyano-2-(trifluoromethyl)indolizin-5-yl)p...)
Affinity DataIC50: 44nMAssay Description:Cells were seeded onto 24-well plates at the density of 2.0×105 cells per well. The cells were incubated at 37° C., 5% CO2 overnight. After approxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
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