BDBM478080 US10889589, EX. # 143

SMILES Cc1c(OC[C@H]2CN(CCO2)C(=O)OC(C)(C)C)nn(c1NC(=O)N[C@H]1[C@H](O)CC(C)(C)c2ccccc12)-c1ccccc1

InChI Key InChIKey=AZKJEBGTKGYLAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478080   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM478080(US10889589, EX. # 143)
Affinity DataIC50: 100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent