BDBM478041 US10889592, Compound I-20

SMILES Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1c(F)cc(cc1F)N1CC2CNCC(C1)O2

InChI Key InChIKey=KVOOLODZUHRJDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478041   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM478041(US10889592, Compound I-20)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM478041(US10889592, Compound I-20)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent