BDBM478038 US10889592, Compound I-15

SMILES C[C@@H](CNC(=O)c1sc2nc(C)cnc2c1N)c1cc(F)c(cc1F)N1C2CCC1CNC2

InChI Key InChIKey=VDBWJHBJMHKNMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478038   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM478038(US10889592, Compound I-15)
Affinity DataIC50: 200nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM478038(US10889592, Compound I-15)
Affinity DataIC50: 6.00E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent