BDBM477658 1-(1-(5-(Ethoxymethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl)azetidin-3-yl)-6-fluoro-1,2,3,4-tetrahydroquinoline 26::US10889569, Example 26

SMILES CCOCc1nnc(N2CC(C2)N2CCCc3cc(F)ccc23)n1-c1ccc(OC)nc1

InChI Key InChIKey=VUHSRUMHHMYMKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477658   

TargetVasopressin V2 receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477658(US10889569, Example 26 | 1-(1-(5-(Ethoxymethyl)-4-...)
Affinity DataIC50: 1.40E+3nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477658(US10889569, Example 26 | 1-(1-(5-(Ethoxymethyl)-4-...)
Affinity DataIC50: 6.10E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent