BDBM477608 (R) N-(1-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-yl)-4-methoxyquinoline-2-carboxamide::US10889564, Example 38

SMILES COc1cc(nc2ccccc12)C(=O)N[C@@H]1CCCc2c1cnn2-c1ccccc1F

InChI Key InChIKey=NJQWRORJKHELLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477608   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Genase Therapeutics

US Patent
LigandPNGBDBM477608(US10889564, Example 38 | (R) N-(1-(2-fluorophenyl)...)
Affinity DataIC50: 2.08E+3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent