BDBM477585 N-[(4R*)-1-(2-fluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-yl]-5-methylpyrazine-2-carboxamide (* putative isomer)::US10889564, Example 15

SMILES Cc1cnc(cn1)C(=O)N[C@@H]1CCCc2c1cnn2-c1ccccc1F

InChI Key InChIKey=MQKZJODEENLOAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477585   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Genase Therapeutics

US Patent
LigandPNGBDBM477585(US10889564, Example 15 | N-[(4R*)-1-(2-fluoropheny...)
Affinity DataIC50: 735nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
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