BDBM477131 US10888567, Compound 42

SMILES Cc1cc(Cl)nc2onc(N)c12

InChI Key InChIKey=FQUKGVSRJVUOPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477131   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM477131(US10888567, Compound 42)
Affinity DataIC50: 1.00E+3nMAssay Description:Recombinant human IDO1 (rhIDO1) was expressed and purified from cultures of EC538 strain of E. coli transformed with pREP4 and pQE9-IDO plasmid. Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM477131(US10888567, Compound 42)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IDO1 in human HeLa cells assessed as inhibition of kynurenine production incubated for 30 mins by microplate reader based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed