BDBM477068 5-(4-((5-chloro-6-(2H-1,2,3- triazol-2-yl)pyridin-3- yl)carbamoyl)-5- (trifluoromethyl)-1H-pyrazol-1- yl)imidazo[1,2-a]pyridine-8- carboxamide::US10888550, Compound 1

SMILES NC(=O)c1ccc(-n2ncc(C(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c2C(F)(F)F)n2ccnc12

InChI Key InChIKey=ASKZDRBTKBSMDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477068   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477068(US10888550, Compound 1 | 5-(4-((5-chloro-6-(2H-1,2...)
Affinity DataIC50: 49nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent