BDBM477047 US10882853, Compound 24

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCC1C[C@H]1CN1CCOCC1

InChI Key InChIKey=XFGZERPQVQABPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477047   

TargetHepatocyte growth factor receptor(Human)
Lanova Medicines

US Patent
LigandPNGBDBM477047(US10882853, Compound 24)
Affinity DataIC50: 25.2nMAssay Description:1. Methods(1) 4 μL of prepared kinase buffer solution or 4 μL of kinase solution (100% inhibition control) were added into a 384-hole plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
Go to US Patent