BDBM477041 US10882853, Compound Foretinib

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)ccnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=JKOLVOLGJWWVFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477041   

TargetHepatocyte growth factor receptor(Human)
Lanova Medicines

US Patent
LigandPNGBDBM477041(US10882853, Compound Foretinib)
Affinity DataIC50: 7.49nMAssay Description:1. Methods(1) 4 μL of prepared kinase buffer solution or 4 μL of kinase solution (100% inhibition control) were added into a 384-hole plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Lanova Medicines

US Patent
LigandPNGBDBM477041(US10882853, Compound Foretinib)
Affinity DataIC50: 14.8nMAssay Description:1. Methods(1) 4 μL of prepared kinase buffer solution or 4 μL of kinase solution (100% inhibition control) were added into a 384-hole plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
Go to US Patent