BDBM477 (2S)-N-[(2S,3R)-4-[(butylcarbamoyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide::(Hydroxyethyl)urea Isostere deriv. 5

SMILES CCCCNC(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=CVKKUZMEEKVVIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research

LigandPNGBDBM477((2S)-N-[(2S,3R)-4-[(butylcarbamoyl)(2-methylpropyl...)
Affinity DataIC50: 126nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM477((2S)-N-[(2S,3R)-4-[(butylcarbamoyl)(2-methylpropyl...)
Affinity DataIC50: 126nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed