BDBM476948 SARS-CoV-2 3CLpro Inhibitors 2k::SARS-CoV-2 3CLpro Inhibitors 2l

SMILES CC(C)C[C@H](NC(=O)OCC12CC3CC(CC(C3)C1)C2)C(=O)NC(CC1CCNC1=O)C=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 476948   

TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM476948(SARS-CoV-2 3CLpro Inhibitors 2l | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 180nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM476948(SARS-CoV-2 3CLpro Inhibitors 2l | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 290nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(MERS-CoV)
Wichita State University

LigandPNGBDBM476948(SARS-CoV-2 3CLpro Inhibitors 2l | SARS-CoV-2 3CLpr...)
Affinity DataIC50: 55nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2021
Entry Details Article
PubMed