BDBM476644 US10870623, Example 13

SMILES COc1ccc(CS[C@@H]2C[C@H](N(C2)C(=O)COc2cc(Cl)cc(Cl)c2)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F)cc1

InChI Key InChIKey=FNNFDGVAQQIDRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476644   

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM476644(US10870623, Example 13)
Affinity DataIC50: 7.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent