BDBM476634 US10875864, EX. 8-73

SMILES Clc1cccc(c1)-c1cnc2ccc(NC3CC[C@@H](CC3)C#N)nn12

InChI Key InChIKey=IALLAFCBZHMLLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476634   

TargetSerine/threonine-protein kinase pim-1(Human)
Sumitomo Dainippon Pharma Oncology

US Patent
LigandPNGBDBM476634(US10875864, EX. 8-73)
Affinity DataIC50: 17nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent