BDBM476591 US10869929, Compound 30::US11554172, Compound 30

SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=Cc6c(C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO)cnn6-c1ccc(OCCCCP(O)(O)=O)cc1

InChI Key InChIKey=JZDXQIACRWWJNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476591   

TargetTSC22 domain family protein 3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476591(US10869929, Compound 30 | US11554172, Compound 30)
Affinity DataIC50: 2.40nMAssay Description:HUT78 cells were cultured in IMEM plus 20% heat inactivated FBS and cell density was maintained between 0.1 to 1.2 million/mL. 786-O cells were cultu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476591(US10869929, Compound 30 | US11554172, Compound 30)
Affinity DataIC50: 2.40nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent