BDBM476581 US10869929, Compound 14::US11554172, Compound 14

SMILES CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCCCP(O)(O)=O

InChI Key InChIKey=VEASGQCTQWVLOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476581   

TargetTSC22 domain family protein 3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476581(US10869929, Compound 14 | US11554172, Compound 14)
Affinity DataIC50: 18.1nMAssay Description:HUT78 cells were cultured in IMEM plus 20% heat inactivated FBS and cell density was maintained between 0.1 to 1.2 million/mL. 786-O cells were cultu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
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TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476581(US10869929, Compound 14 | US11554172, Compound 14)
Affinity DataIC50: 18.1nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent