BDBM47658 1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl)urea::1-(4-methylphenyl)-3-[2-(3-pyridinyl)-4-pyrimidinyl]urea::1-(p-tolyl)-3-[2-(3-pyridyl)pyrimidin-4-yl]urea::MLS000706883::N-(4-methylphenyl)-N'-[2-(3-pyridinyl)-4-pyrimidinyl]urea::SMR000335712::cid_1477566

SMILES Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1

InChI Key InChIKey=FCFZSPVQFIPQML-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47658   

LigandPNGBDBM47658(cid_1477566 | 1-(4-methylphenyl)-3-(2-pyridin-3-yl...)
Affinity DataEC50:  2.07E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM47658(cid_1477566 | 1-(4-methylphenyl)-3-(2-pyridin-3-yl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed