BDBM476559 (8 endo)-3-(5-methyl-1,3,4-oxadiazol-2-yl)-3-azabicyclo[3.2.1]octan-8-amine::US10875854, Example 32
SMILES CC(C)c1ccc(O[C@@H](C)C(F)(F)F)n2nc(N[C@H]3[C@H]4CC[C@@H]3CN(C4)c3nnc(C)o3)nc12
InChI Key
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 476559
TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Human)
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 43.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
