BDBM476548 3-methoxy-4-(2-methyl-4-pyridyl)aniline::US10875854, Example 21

SMILES COc1cc(Nc2nc3c(ccc(OCC(F)(F)F)n3n2)C(C)C)ccc1-c1ccnc(C)c1

InChI Key InChIKey=IRYZVZCQYAJCFN-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476548   

TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Human)
Hoffmann-La Roche

US Patent

LigandBDBM476548(US10875854, Example 21 | 3-methoxy-4-(2-methyl-4-p...)Copy SMILESCopy InChI

Affinity DataEC50:  21.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2021
Entry Details
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