BDBM476547 5-Amino-2-(4-methylimidazol-1-yl)benzonitrile::US10875854, Example 20

SMILES CC(C)c1ccc(OCC(F)(F)F)n2nc(Nc3ccc(c(c3)C#N)-n3cnc(C)c3)nc12

InChI Key InChIKey=FJYFUVMUDIKNIS-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476547   

TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Human)
Hoffmann-La Roche

US Patent

LigandBDBM476547(US10875854, Example 20 | 5-Amino-2-(4-methylimidaz...)Copy SMILESCopy InChI

Affinity DataEC50:  49.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2021
Entry Details
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