BDBM476537 2-(2-((3-(difluoromethoxy)-4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)amino)-5-(2,2,2-trifluoroethoxy)-[1,2,4]triazolo pyridin-8-yl)propan-2-ol::US10875854, Example 10

SMILES Cc1ncn(n1)-c1ccc(Nc2nc3c(ccc(OCC(F)(F)F)n3n2)C(C)(C)O)cc1OC(F)F

InChI Key InChIKey=QZSIPBCKPNRHIG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476537   

LigandPNGBDBM476537(US10875854, Example 10 | 2-(2-((3-(difluoromethoxy...)
Affinity DataEC50:  45.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent