BDBM476529 N-((8 endo)-3-(3-methylisothiazol-5-yl)-3-azabicyclo[3.2.1]octan-8-yl)-5-(2,2,2-trifluoroethoxy)-[1,2,4]triazolo[1,5-a]pyridin-2-amine::US10875854, Example 2

SMILES Cc1cc(sn1)N1C[C@@H]2CC[C@H](C1)[C@H]2Nc1nc2cccc(OCC(F)(F)F)n2n1

InChI Key InChIKey=ROMJDAAIEWRTMY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476529   

LigandPNGBDBM476529(N-((8 endo)-3-(3-methylisothiazol-5-yl)-3-azabicyc...)
Affinity DataEC50:  7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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